I think you can minimize scope failure by adjusting the gas port size so that your brass doesn't exit the weapon and go into orbit. On my 581 mini my brass easily went 30 to 40ft into the woods. I reduced the gas port to about .045 and now my brass goes about 8 to 10 ft and I can actually find it. The .080 gas port just pounded the weapon unnecessarily. With the reduced gas port it's a much more pleasant weapon to shoot which is a bonus for the wife.
I had a scope and red dot that were at the lower end of the scale from a major manufacture . destroyed them both . installed a buffer and used a couple of better quality scopes I have laying around and it made all the difference in the world . the bottom line is dont expect the 50.00 centerpoint red dot or tasco 3x9 to last long on a mini.
Don't know if it made a difference, but I went with a fixed 4x shotgun scope on one of my minis, and installed a buffer (which I had to thin A LOT before it worked right). It's had many thousands pounded through it with no problem.
My Weaver Classic V 1-3x has had no issues in 400 or so rounds. Its often used for heavy recoil dangerous game rifles, but I don't know if that necessarily helps with the mini's bang-clank-clank shaking of the receiver. Still though, not a problem yet.
1911 buffers front and rear and they sure calm the rifle down a lot. I had over a thousand rounds on a Gamo 3x9 Air Rifle scope that out lived the air rifle and is still in one piece. Original gas port bushing. Start with the buffers and see how much smoother the gun shoots. Not a big deal to have to adjust the scope a little.
Like glenwatkins, mine has been very easy on my Wilson buffer, but I only have one on the rear. It only has some light 'dents' in it after a few hundred rounds, and looks like it will hold up for another thousand. Even if it doesn't, I have five more from the pack of six I bought so for $10 its basically a non-expense for the life of the rifle.
I did not notice a change in point of impact with my scope, just less erratic groups. I really think the Weaver Classic V scopes are great, they've never shifted POI on me, and re-sighting in seems to be spot on. They're clear out to the edges and the fine crosshairs at 3x are good enough for precise paper punching at 50 yards.