I am not sure of the cost against an S&W, but my vote for both a weapon that you and your wife can handle is the Glock 23. This is 40 cal. and will have knock down power. It is a very light weapon and yet has very good qualities and durability. The females (and detectives) on our department carry this weapon and have no problems in handling them. We just returned from the firing range and had 16 Glocks firing. We fired over 5000 rounds with one stovepipe. That’s a pretty good report. The weapon is a single action, so it acts just like a wheel gun,(course the wheel gun will not stovepipe) but is still just as safe as a double/single action semi-auto.