Hi, I have a number of revolvers and semiautos. If a firearm is not convenient to carry, it won't be carried. I like my .45LCs and .45 ACPs, but find my .38 Special S&W lightweight (11oz) 337 easy and convenient to carry in a front jeans pocket. Equipped with a laser grip sight that allows firing from any position or hand brings value to carrying the somewhat low power P+ .38 special 5-shot. Getting hits on a critical area is more important than caliber.
If I know for sure that I will need a gun, I will always take a rifle, not a handgun.